Brain Imaging Center (2000-2020) at the Helen Wills Neuroscience Institute at the University of California, Berkeley. Further studies are needed to determine whether the changes in coactivation and modularity that are associated with alcohol abstinence are causal features of alcohol dependence or a consequence of excessive drinking and alcohol exposure. I completed my Ph.D. with Tobias Egner at Duke, and postdoctoral research with Mark D’Esposito at UC Berkeley. He combines behavioral experiments, computational modeling and neuroimaging to study how reward and motivation interacts with cognitive processes to shape everyday behavior. Although our understanding of the neurocircuitry that underlies alcohol use has improved, novel brain regions that are involved in alcohol use and novel biomarkers of alcohol use need to be identified. I use the methods of cognitive neuroscience to address questions about the interactions between perception, attention, memory, and action. The D'Esposito Lab is a cognitive neuroscience research laboratory within theHelen Wills Neuroscience Institute and the Department of Psychology. Schedule: Mondays, 3:00pm - 5:00pm. Advisors: Carla L. Hudson Kam & Mark D’Esposito Dissertation: The sensitive period for language acquisition: The role of age related differences in cognitive and neural function B.A. Building on this previous work, we implemented the DDM as the choice rule in inter-temporal choice (temporal discounting) and risky choice (probability discounting) using hierarchical Bayesian parameter estimation. He completed post-doctoral fellowships at Indiana University with Joshua Brown, and the University of California, Berkeley with Mark D'Esposito. Copyright © 2020 UC Regents; all rights reserved, UCSF Weill Institute for Neurosciences and Director, UCSF Neurorecovery Clinic, The Lactate Shuttle Theory: Relevance for Traumatic Brain Injury & More. The aim of the current study was to investigate the oscillatory neuronal mechanisms underlying two distinct components of hierarchical cognitive control: the level of abstraction of a rule, and the number of rules that must be maintained (set-size). Prioritizing relevant information has been linked to theta frequency neural oscillations in lateral prefrontal cortex and suppressing irrelevant information has been linked to alpha oscillations in occipito-parietal cortex [3,11]. He subsequently started as a post-doctoral researcher in the lab of Professor Mark D’Esposito at UC Berkeley, focusing on cognitive control processes that are engaged during learning and memory. I am trained as a cognitive neuroscientist and experimental psychologist. Bio: Dr. Mark D’Esposito is Professor of Neuroscience and Psychology, and founding Director of the Henry H. Wheeler, Jr. Finally, the expression of beta amplitude was coordinated via the phase of delta oscillations, and theta phase coupled with gamma amplitude. Hwang, K, Shine JM, Cellier D, D'Esposito M. 2020. Drawing on his training in Neurology, Neuroscience and Psychology, his research focuses on investigating the neural bases of high-level cognitive processes such as working memory and cognitive control, achieved through several different experimental approaches and methodologies. Many hub brain regions that control this network were identified, including several that have been previously overlooked in alcohol research. Analyses of DDM parameters revealed that patients showed substantially increased non-decision times and reduced response caution during risky choice. Structuring of the alcohol abstinence network revealed three major brain modules: 1) extended amygdala module, 2) midbrain striatal module, and 3) cortico-hippocampo-thalamic module, reminiscent of the three-stage theory. I would like to also thank my advisor Mark D’Esposito for taking me into his lab so completely even though I did not begin graduate school working with him. - The Object Perception Lab at Vanderbilt University has an article which discusses specialized systems vs. expertise Cognitive Control and High-Level Cognition Narrated Videos- Leveraging graph theory to understand the large-scale organization of cognitive control Mark D'Esposito Mark D'Esposito is a professor of Neuroscience and Psychology at the Helen Wills Neuroscience Institute. We validated our approach in data from nine patients with focal lesions to the ventromedial prefrontal cortex / medial orbitofrontal cortex (vmPFC/mOFC) and nineteen age- and education-matched controls. constant encouragement of the D’Esposito lab and my graduate advisor, Mark D’Esposito. He is also an attending neurologist at the Northern California VA Health Care System and Adjunct Professor of Neurology at UCSF. Magnetic induction has the distinct advantage, compared to scalp electrode methods, of producing much larger electric field amplitudes in the brain for similar electric field amplitudes in the scalp. I am also interested in using functional MRI to observe non-invasive brain stimulation with magnetic induction in situ, which requires developing new hardware and software that minimizes the interactions between these two methods. Brain Imaging Center at the Helen Wills Neuroscience Institute at the University of California, Berkeley. The D'Esposito Lab is a cognitive neuroscience research laboratory within the Helen Wills Neuroscience Institute and the Department of Psychology. In 2016, she was awarded an NIH postdoctoral fellowship to examine the representational properties and causal mechanisms of lateral prefrontal function in emotion with Dr. Mark D'Esposito at the University of California, Berkeley. Competition and Control During Working Memory. We found distinct oscillatory signatures that correspond to two different components of hierarchical control: the level of abstraction of a rule and the number of rules in competition. Justin Riddle is a graduate student at University of California, Berkeley studying cognitive neuroscience under the supervision of Professor Mark D’Esposito. My research aims to provide insights into brain metabolism in healthy aging using advanced 1H MR spectroscopy (MRS) methods. Mark D’Esposito, Helen Wills Neuroscience Institute, University of California, Berkeley “A neural blueprint for cognitive control” Thursday January 26, 12:30-1:30pm Howell Hall 205. Georgia Institute of Technology Lab Website: rahnevlab.gatech.edu 130 J.S. I recently began to investigate markers for brain metabolism using spectroscopy data and the potential changes in stroke patients. ... Mark D’Esposito. Article Causal Contribution of Awake Post-encoding Processes to Episodic Memory Consolidation Arielle Tambini1,2,3,* and Mark D’Esposito1 1Helen Wills Neuroscience Institute and Department of Psychology, University of California, Berkeley, Berkeley, CA 94720, USA 2Department of Neurobiology and Behavior, Center for Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA John Gabrieli. Kimbrough, A, Lurie DJ, Collazo A, Kreifeldt M, Sidhu H, Macedo GC, D'Esposito M, Contet C, George O. Riddle, J, Scimeca JM, Cellier D, Dhanani S, D'Esposito M. Riddle, J, Vogelsang DA, Hwang K, Cellier D, D'Esposito M. Brain-wide functional architecture remodeling by alcohol dependence and abstinence. E.A. The drift diffusion model as the choice rule in inter-temporal and risky choice: A case study in medial orbitofrontal cortex lesion patients and controls. Jacobs completed her thesis in the lab of Mark D’Esposito on the effects of estrogen on dopamine-dependent cognitive processes. Dan continued his research career at the University of California, Berkeley working on functional brain imaging in the lab of Mark D’Esposito. MOOC: Algorithms - Design and Analysis, Part 1. I’m a postdoctoral fellow in Dr. Mark D’Esposito’s lab at the University of California, Berkeley. Working memory (WM) relies on the prioritization of relevant information and suppression of irrelevant information [1, 2]. Brain Imaging Center. Assistant Professor within the Department of Psychiatry and Behavioral Sciences and the Director of the Stanford Brain Stimulation Lab. The D'Esposito Lab is a cognitive neuroscience research laboratory within the. Professor, Neurological Surgery, UCSF Weill Institute for Neurosciences, Professor, Department of Integrative Biology, UC Berkeley, The Lactate Shuttle Theory: Relevance for Traumatic Brain Injury & More (interview), Professor of the Graduate School, Department of Physics, UC Berkeley, Professor, Department of Bioengineering, Electrical Engineering & Computer Science, UC Berkeley. Both theta and delta amplitude correlated with behavioral performance in the tasks but in an opposite manner: theta correlated with response time slowing when the number of rules increased whereas delta correlated with response time when rules became more abstract. Mark D’Esposito, MD Professor of Neuroscience and Psychology, and Director of the Henry H. Wheeler, Jr. These results identify brain targets for future research and demonstrate that alcohol use and dependence remodel brain-wide functional architecture to decrease modularity. Here, we used a retrospective-cue WM paradigm to manipulate prioritization and suppression task demands designed to drive theta oscillations in prefrontal cortex and alpha oscillations in parietal cortex, respectively. Research Sasha Gibbs, a graduate student in Mark D’Esposito’s lab, and HWNI physicist Charlene Tan show off the fMRI machine at the Wheeler Brain Imaging Center. I am investigating abnormal cerebral perfusion and what it means for behavior after stroke. I’ve learned so much from every lab member, and I’m grateful for everyone who has made the lab such an enjoyable place to work. Goard completed his thesis in Yang Dan’s lab on cholinergic neuromodulation of visual perception. Causal Evidence for a Role of Theta and Alpha Oscillations in the Control of Working Memory. Oscillatory amplitude correlated with behavioral performance in the task. I am collaborating with members of Mark D’Esposito’s lab on the analysis of several different types of resting state data, and in the process we are developing new software tools that will be made available as part of the open-source NiPy project. The effect of rhythmic TMS on WM performance was dependent on whether the TMS frequency matched or mismatched the expected underlying task-driven oscillations of the targeted region. Dr. Mark D’Esposito is Professor of Neuroscience and Psychology, and former Director of the Henry H. Wheeler, Jr. My research interests broadly include the role of attention and memory on category learning as well as the perception of emotional expressions. A time varying magnetic field, produced by a coil placed on the head, induces an electric field within the brain which couples to neurons and potentially affects their short and long term behavior. Speaker: Mark D'Esposito, MD Professor of Neuroscience and Psychology, University of California, Berkeley, USA. In contrast, vmPFC/mOFC damage abolished neither scaling nor asymptote of the drift rate. Our project-oriented (ad hoc) teams are driven to provide new tools in medicine or to improve existing tools, and to deploy them in the most efficient way possible, whether through blogs, peer-reviewed publications, patents or startup companies. In the lab, I am responsible for fMRI task design, data collection and analysis for the Decision-Making in Alzheimer’s and Related Dementias and the Online Studies of Decision-Making in Healthy Aging projects. We collected electroencephalography (EEG) data in 31 men and women who performed a hierarchical cognitive control task that varied in levels of abstraction and set-size. To causally test the role of these neural oscillations, we applied rhythmic transcranial magnetic stimulation (TMS) in either theta or alpha frequency to prefrontal and parietal regions identified using functional MRI. Cooper, U. Hasson, and S.L. My main interest is the non-invasive stimulation of the brain by magnetic induction. In 2018, she co-edited the 2nd edition of The Nature of Emotion: Fundamental Questions. Brian Galla. At present, I am developing methods to study glucose metabolism, brain thermometry, and the brain-gut axis. I use methods such as structural and functional MRI, perfusion and diffusion MRI, and spectroscopy. Abstract: A fundamental question in cognitive neuroscience is how we are able to flexibly guide our behavior. In the years before grad school, I worked in homeless counseling and mental health services. Interpretation-Mediated Changes in Neural Activity During Language Comprehension. Collectively, I aim to use these neural markers to predict recovery and rehabilitation. Angela Duckworth. The present study used a single-cell whole-brain imaging approach to 1) assess whether abstinence from alcohol in an animal model of alcohol dependence alters the functional architecture of brain activity and modularity, 2) validate our current knowledge of the neurocircuitry of alcohol abstinence, and 3) discover brain regions that may be involved in alcohol use. Director Mark D'Esposito, MD Professor of Neuroscience & Psychology Dr. Lana Kaiser, PhD. Associate Professor in Psychiatry, Harvard Medical School and Associate Biophysicist at McLean Hospital, Belmont MA. Small. I am a recent graduate from the Psychology Specialist program at the University of Toronto. These results suggest that distinct neural oscillatory mechanisms underlie different components of hierarchical cognitive control. University of Wisconsin—Madison, 2002 Psychology, English Advisor: Jenny R. Saffran Dr. D’Esposito’s lab investigates the neurophysiological and neurochemical mechanisms underlying cognition, how the brain recovers from injury and potential treatments for the injured brain. Together, these results causally establish dissociable roles for prefrontal theta oscillations and parietal alpha oscillations in the control of internally maintained WM representations. Lab Manager Hello! Distinct oscillatory dynamics underlie different components of hierarchical cognitive control. The first step was to determine a referencing system capable of discriminating between the small chemical shifts of complex, overlapping metabolite patterns, which was achieved with a small molecule sold as a nutritional supplement. Coon Building Blog: rahnevlab.wordpress.com Atlanta, GA 30332 Twitter: @DobyRahnev ACADEMIC POSITIONS 2015-present Assistant Professor, School of Psychology, Georgia Tech 2012-2015 Postdoc in Cognitive Neuroscience, UC Berkeley (Advisor: Mark D’Esposito) EDUCATION Hierarchical cognitive control enables us to execute actions guided by abstract goals. Not currently active. Mark D'Esposito is a Professor of Neuroscience and Psychology. Posterior predictive checks confirmed that this model provided a superior account of the relationship between value and RT. Description. Baniqued completed an NIH post-doctoral fellowship at the University of California, Berkeley, in the lab of Mark D’Esposito. Mark has challenged me to think fully about questions that I had thought were outside my arena. 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